dextromethorphan

URI: https://gptkb.org/entity/dextromethorphan

GPTKB entity

Statements (65)

Predicate	Object
gptkbp:instanceOf	gptkb:NMDA_receptor_antagonist gptkb:drug gptkb:antitussive
gptkbp:abusedAs	gptkb:dissociative_drug
gptkbp:abusePotential	yes
gptkbp:ATCCode	R05DA09
gptkbp:brand	gptkb:Coricidin gptkb:Delsym gptkb:NyQuil gptkb:Robitussin gptkb:Vicks_44
gptkbp:broadcastOn	unscheduled (US)
gptkbp:CASNumber	125-71-3
gptkbp:category	gptkb:recreational_drug gptkb:dissociative gptkb:over-the-counter_drug antitussive agent
gptkbp:cause	gptkb:serotonin_syndrome
gptkbp:chemicalFormula	C18H25NO
gptkbp:contraindication	MAOI use allergy to dextromethorphan
gptkbp:developedBy	gptkb:Roche
gptkbp:discoveredIn	1953
gptkbp:foundIn	tablets powder capsules cough syrups lozenges
gptkbp:has_stereochemistry	gptkb:levomethorphan
gptkbp:interactsWith	gptkb:MAO_inhibitors gptkb:SSRIs CYP2D6 inhibitors CYP3A4 inhibitors
gptkbp:IUPACName	(4aS,10,10aR)-6-methoxy-11-methyl-1,2,3,4,4a,9,10,10a-octahydro-7H-10,4a-(epiminoethano)phenanthrene
gptkbp:legalStatus	OTC in many countries
gptkbp:MeSH_ID	D003962
gptkbp:metabolism	gptkb:CYP2D6 gptkb:dextrorphan
gptkbp:molecularWeight	271.4 g/mol
gptkbp:overdoseSymptoms	seizures dissociation respiratory depression hallucinations agitation
gptkbp:pregnancyCategory	gptkb:C_(Australia) C (US)
gptkbp:PubChem_CID	5360696 CHEMBL651 DB00514
gptkbp:relatedTo	gptkb:codeine gptkb:levorphanol gptkb:phencyclidine gptkb:opioid
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	confusion nausea vomiting dizziness drowsiness
gptkbp:UNII	7355X3RO96
gptkbp:usedFor	cough suppression treatment of cough
gptkbp:bfsParent	gptkb:memantine
gptkbp:bfsLayer	5
https://www.w3.org/2000/01/rdf-schema#label	dextromethorphan