|
gptkbp:instanceOf
|
gptkb:drug
NMDA receptor antagonist
antitussive
|
|
gptkbp:abusedAs
|
dissociative drug
|
|
gptkbp:abusePotential
|
yes
|
|
gptkbp:ATCCode
|
R05DA09
|
|
gptkbp:brand
|
gptkb:Coricidin
gptkb:Delsym
gptkb:NyQuil
gptkb:Robitussin
gptkb:Vicks_44
|
|
gptkbp:broadcastOn
|
unscheduled (US)
|
|
gptkbp:CASNumber
|
125-71-3
|
|
gptkbp:category
|
recreational drug
antitussive agent
dissociative
over-the-counter drug
|
|
gptkbp:cause
|
gptkb:serotonin_syndrome
|
|
gptkbp:chemicalFormula
|
C18H25NO
|
|
gptkbp:contraindication
|
MAOI use
allergy to dextromethorphan
|
|
gptkbp:developedBy
|
gptkb:Roche
|
|
gptkbp:discoveredIn
|
1953
|
|
gptkbp:foundIn
|
tablets
powder
capsules
cough syrups
lozenges
|
|
gptkbp:has_stereochemistry
|
gptkb:levomethorphan
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
dextromethorphan
|
|
gptkbp:interactsWith
|
gptkb:MAO_inhibitors
gptkb:SSRIs
CYP2D6 inhibitors
CYP3A4 inhibitors
|
|
gptkbp:IUPACName
|
(4aS,10,10aR)-6-methoxy-11-methyl-1,2,3,4,4a,9,10,10a-octahydro-7H-10,4a-(epiminoethano)phenanthrene
|
|
gptkbp:legalStatus
|
OTC in many countries
|
|
gptkbp:MeSH_ID
|
D003962
|
|
gptkbp:metabolism
|
gptkb:CYP2D6
gptkb:dextrorphan
|
|
gptkbp:molecularWeight
|
271.4 g/mol
|
|
gptkbp:overdoseSymptoms
|
seizures
dissociation
respiratory depression
hallucinations
agitation
|
|
gptkbp:pregnancyCategory
|
gptkb:C_(Australia)
C (US)
|
|
gptkbp:PubChem_CID
|
5360696
CHEMBL651
DB00514
|
|
gptkbp:relatedTo
|
gptkb:codeine
gptkb:levorphanol
gptkb:phencyclidine
opioid
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
confusion
nausea
vomiting
dizziness
drowsiness
|
|
gptkbp:UNII
|
7355X3RO96
|
|
gptkbp:usedFor
|
cough suppression
treatment of cough
|
|
gptkbp:bfsParent
|
gptkb:memantine
|
|
gptkbp:bfsLayer
|
5
|