serotonin 5-HT2B receptor

URI: https://gptkb.org/entity/serotonin_5-HT2B_receptor
GPTKB entity
Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:activatedBy gptkb:phospholipase_C
gptkbp:alternativeName gptkb:5-HT2B_receptor
HTR2B
serotonin receptor 2B
gptkbp:associatedWith valvular heart disease
gptkbp:binds serotonin
gptkbp:couplingType Gq/11 protein
gptkbp:encodedBy HTR2B gene
gptkbp:enemyOf RS-127445
norfenfluramine
ritanserin
BW 723C86
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
brain
heart
liver
stomach
gptkbp:foundIn gptkb:human
gptkb:mouse
right
https://www.w3.org/2000/01/rdf-schema#label serotonin 5-HT2B receptor
gptkbp:involvedIn migraine
vasoconstriction
cardiac development
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome 2q37.1
gptkbp:memberOf 5-HT2 receptor family
gptkbp:OMIM 601358
gptkbp:PDB 4IB4
gptkbp:regulates cell proliferation
fibrosis
smooth muscle contraction
gptkbp:target gptkb:lorcaserin
gptkb:MDMA
gptkb:ergotamine
gptkb:trazodone
LSD
antipsychotics
psychoactive drugs
antidepressants
hallucinogens
mirtazapine
methysergide
fenfluramine
gptkbp:UniProtID P41595
gptkbp:bfsParent gptkb:CHEMBL2105727
gptkbp:bfsLayer 7