Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activatedBy |
APC/C-mediated securin degradation
|
| gptkbp:biologicalProcess |
cysteine endopeptidase activity
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:EC_number |
3.4.22.49
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
cleaves cohesin
|
| gptkbp:gene |
gptkb:ESPL1
|
| https://www.w3.org/2000/01/rdf-schema#label |
separase
|
| gptkbp:involvedIn |
cell division
anaphase |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae gptkb:Homo_sapiens |
| gptkbp:regulates |
gptkb:securin
gptkb:cyclin-dependent_kinases sister chromatid separation |
| gptkbp:role |
meiosis
mitosis |
| gptkbp:substrate |
gptkb:cohesin_complex
|
| gptkbp:bfsParent |
gptkb:cohesin_complex
|
| gptkbp:bfsLayer |
6
|