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gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alsoKnownAs
|
gptkb:angiotensinogenase
|
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gptkbp:CASNumber
|
9001-60-9
|
|
gptkbp:discoveredBy
|
gptkb:Per_Bergman
gptkb:Robert_Tigerstedt
|
|
gptkbp:discoveredIn
|
1898
|
|
gptkbp:EC_number
|
3.4.23.15
|
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gptkbp:encodedBy
|
gptkb:REN_gene
|
|
gptkbp:foundIn
|
gptkb:kidney
gptkb:juxtaglomerular_cells
|
|
gptkbp:function
|
regulates blood pressure
catalyzes conversion of angiotensinogen to angiotensin I
regulates electrolyte balance
|
|
gptkbp:GO_term
|
gptkb:GO:0004193
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
renin
|
|
gptkbp:inhibitedBy
|
gptkb:angiotensin_II
gptkb:aldosterone
high blood pressure
|
|
gptkbp:molecularWeight
|
~37 kDa
|
|
gptkbp:partOf
|
gptkb:renin-angiotensin_system
|
|
gptkbp:producedBy
|
humans
mammals
|
|
gptkbp:promotion
|
sympathetic nervous system
low blood pressure
low sodium concentration
|
|
gptkbp:secretes
|
gptkb:juxtaglomerular_apparatus
|
|
gptkbp:significance
|
measured in diagnosis of hypertension
measured in diagnosis of primary aldosteronism
|
|
gptkbp:structureType
|
gptkb:protein
|
|
gptkbp:UniProtID
|
gptkb:P00797
|
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gptkbp:bfsParent
|
gptkb:kidney
|
|
gptkbp:bfsLayer
|
5
|