Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hormone
mineralocorticoid |
| gptkbp:actsOn |
gptkb:kidney
colon sweat glands salivary glands |
| gptkbp:associatedWith |
gptkb:Conn's_syndrome
Addison's disease hyperaldosteronism hypoaldosteronism |
| gptkbp:biosynthesized_from |
cholesterol
|
| gptkbp:CASNumber |
52-39-1
|
| gptkbp:category |
hormone
endocrine system adrenal hormone |
| gptkbp:chemicalFormula |
C21H28O5
|
| gptkbp:discoveredBy |
Simpson and Tait
|
| gptkbp:discoveredIn |
1953
|
| gptkbp:excretion |
gptkb:kidney
|
| gptkbp:function |
increases blood pressure
increases blood volume increases potassium excretion increases sodium retention increases water retention |
| gptkbp:halfLife |
20 minutes
|
| https://www.w3.org/2000/01/rdf-schema#label |
aldosterone
|
| gptkbp:inhibitedBy |
dopamine
atrial natriuretic peptide |
| gptkbp:meltingPoint |
166-168 °C
|
| gptkbp:MeSH_ID |
D000437
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
360.44 g/mol
|
| gptkbp:predecessor |
gptkb:corticosterone
|
| gptkbp:producedBy |
adrenal cortex
zona glomerulosa |
| gptkbp:promotion |
gptkb:angiotensin_II
increased potassium |
| gptkbp:PubChem_CID |
5839
CHEBI:27584 |
| gptkbp:recipient |
mineralocorticoid receptor
|
| gptkbp:regulates |
blood pressure
sodium reabsorption water balance potassium excretion |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:UNII |
U5SYW4725M
|
| gptkbp:bfsParent |
gptkb:renin
gptkb:Renin-angiotensin_system gptkb:Corticosteroid gptkb:hormone |
| gptkbp:bfsLayer |
6
|