|
gptkbp:instanceOf
|
gptkb:mineralocorticoid
gptkb:hormone
|
|
gptkbp:actsOn
|
gptkb:kidney
colon
sweat glands
salivary glands
|
|
gptkbp:associatedWith
|
gptkb:Conn's_syndrome
Addison's disease
hyperaldosteronism
hypoaldosteronism
|
|
gptkbp:biosynthesized_from
|
cholesterol
|
|
gptkbp:CASNumber
|
52-39-1
|
|
gptkbp:category
|
gptkb:hormone
endocrine system
adrenal hormone
|
|
gptkbp:chemicalFormula
|
C21H28O5
|
|
gptkbp:discoveredBy
|
Simpson and Tait
|
|
gptkbp:discoveredIn
|
1953
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:function
|
increases blood pressure
increases blood volume
increases potassium excretion
increases sodium retention
increases water retention
|
|
gptkbp:halfLife
|
20 minutes
|
|
gptkbp:inhibitedBy
|
dopamine
atrial natriuretic peptide
|
|
gptkbp:meltingPoint
|
166-168 °C
|
|
gptkbp:MeSH_ID
|
D000437
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
360.44 g/mol
|
|
gptkbp:predecessor
|
gptkb:corticosterone
|
|
gptkbp:producedBy
|
adrenal cortex
zona glomerulosa
|
|
gptkbp:promotion
|
gptkb:angiotensin_II
increased potassium
|
|
gptkbp:PubChem_CID
|
5839
CHEBI:27584
|
|
gptkbp:recipient
|
mineralocorticoid receptor
|
|
gptkbp:regulates
|
blood pressure
sodium reabsorption
water balance
potassium excretion
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:UNII
|
U5SYW4725M
|
|
gptkbp:bfsParent
|
gptkb:steroid_hormone_biosynthesis
gptkb:renin
gptkb:renin-angiotensin_system
gptkb:C21H34O4
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
aldosterone
|