|
gptkbp:instanceOf
|
peptide
|
|
gptkbp:actsOn
|
angiotensin II receptor type 1
angiotensin II receptor type 2
|
|
gptkbp:CASNumber
|
gptkb:4474-91-3
|
|
gptkbp:chemicalFormula
|
C50H71N13O12
|
|
gptkbp:discoveredBy
|
gptkb:Irvine_H._Page
gptkb:Eduardo_Braun-Menéndez
1939
|
|
gptkbp:foundIn
|
humans
mammals
|
|
gptkbp:function
|
vasoconstriction
increases blood pressure
stimulates aldosterone secretion
stimulates antidiuretic hormone release
stimulates thirst
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
angiotensin II
|
|
gptkbp:improves
|
sodium reabsorption
sympathetic activity
|
|
gptkbp:MeSH_ID
|
gptkb:D000881
|
|
gptkbp:molecularWeight
|
1046.2 g/mol
|
|
gptkbp:opposedBy
|
gptkb:angiotensin_receptor_blockers
ACE inhibitors
|
|
gptkbp:part_of
|
gptkb:renin-angiotensin_system
|
|
gptkbp:predecessor
|
gptkb:angiotensin_I
|
|
gptkbp:producedBy
|
gptkb:angiotensin-converting_enzyme
|
|
gptkbp:promotion
|
cardiac hypertrophy
vascular smooth muscle cell growth
|
|
gptkbp:PubChem_CID
|
gptkb:CHEBI:2719
|
|
gptkbp:sequence
|
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
|
|
gptkbp:UNII
|
X0I9GH1L0X
|
|
gptkbp:usedFor
|
vasopressor agent
|
|
gptkbp:bfsParent
|
gptkb:ACE2
|
|
gptkbp:bfsLayer
|
5
|