phospholipase C family

GPTKB entity

Statements (40)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy gptkb:G_protein-coupled_receptors
gptkb:receptor_tyrosine_kinases
gptkbp:catalyzes cleavage of phosphatidylinositol 4,5-bisphosphate
gptkbp:discoveredBy gptkb:Earl_W._Sutherland_Jr.
gptkbp:domain gptkb:EF_hand_domain
gptkb:PH_domain
C2 domain
X and Y catalytic domains
gptkbp:EC_number 3.1.4.11
gptkbp:foundIn gptkb:Bacteria
eukaryotes
gptkbp:function hydrolyzes phospholipids
gptkbp:gene gptkb:PLCE
gptkb:PLCH
PLCB
PLCD
PLCG
PLCL
PLCZ
https://www.w3.org/2000/01/rdf-schema#label phospholipase C family
gptkbp:involvedIn signal transduction
gptkbp:member phospholipase C beta
phospholipase C delta
phospholipase C epsilon
phospholipase C eta
phospholipase C gamma
phospholipase C zeta
gptkbp:product gptkb:inositol_trisphosphate
diacylglycerol
gptkbp:relatedTo calcium signaling
phosphoinositide signaling
gptkbp:bfsParent gptkb:PLCγ
gptkb:PLCE1
gptkb:PLCG2
gptkb:PLCB2
gptkb:PLCB3
gptkb:PLCD1
gptkb:PLCD3
gptkbp:bfsLayer 7