valosin-containing protein

URI: https://gptkb.org/entity/valosin-containing_protein
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:CDC48_homolog
gptkb:p97
transitional endoplasmic reticulum ATPase
gptkbp:associatedWith gptkb:multisystem_proteinopathy
amyotrophic lateral sclerosis
inclusion body myopathy with Paget disease and frontotemporal dementia
gptkbp:biologicalProcess ATP binding
protein binding
ubiquitin binding
gptkbp:cellularComponent gptkb:endoplasmic_reticulum
gptkb:nucleus
gptkb:cytoplasm
gptkbp:discoveredBy 1994
gptkbp:family gptkb:AAA_ATPase_family
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:function protein degradation
ubiquitin-dependent protein catabolic process
ATPase activity
gptkbp:gene gptkb:VCP
gptkbp:GO_term gptkb:GO:0006457_(protein_folding)
GO:0005524 (ATP binding)
GO:0006511 (ubiquitin-dependent protein catabolic process)
https://www.w3.org/2000/01/rdf-schema#label valosin-containing protein
gptkbp:interactsWith gptkb:PLAA
gptkb:NPL4
gptkb:UFD1L
gptkb:atlastin-1
gptkb:UBXN1
gptkbp:involves DNA repair
cell cycle regulation
autophagy
endoplasmic reticulum-associated degradation
gptkbp:locatedOnChromosome gptkb:chromosome_9p13.3
gptkbp:molecularWeight 97 kDa
gptkbp:number_of_amino_acids 806
gptkbp:OMIM 601023
gptkbp:orthologInYeast gptkb:CDC48
gptkbp:PDB gptkb:5FTK
gptkbp:postTranslationalModification phosphorylation
sumoylation
ubiquitination
gptkbp:structure hexamer
gptkbp:subunit homohexamer
gptkbp:UniProtID gptkb:P55072
gptkbp:bfsParent gptkb:p97/VCP
gptkbp:bfsLayer 7