p38 mitogen-activated protein kinases

URI: https://gptkb.org/entity/p38_mitogen-activated_protein_kinases
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:activatedBy environmental stress
pro-inflammatory cytokines
dual phosphorylation on threonine and tyrosine residues
gptkbp:alsoKnownAs gptkb:MAPK_p38
gptkb:Mitogen-activated_protein_kinase_14
gptkbp:biologicalProcess serine/threonine kinase activity
gptkbp:discoveredIn 1994
gptkbp:encodedBy gptkb:MAPK14_gene
gptkbp:hasIsoform MAPK11 (p38β)
MAPK12 (p38γ)
MAPK13 (p38δ)
MAPK14 (p38α)
gptkbp:involvedIn apoptosis
cell differentiation
inflammatory response
cellular response to stress
gptkbp:involves gptkb:cancer
neurodegenerative diseases
rheumatoid arthritis
gptkbp:locale gptkb:nucleus
gptkb:cytoplasm
gptkbp:memberOf gptkb:MAPK_family
gptkbp:orthologIn gptkb:human
gptkb:mouse
gptkb:right
gptkbp:phosphorylates transcription factors
cytoskeletal proteins
protein kinases
gptkbp:regulates gptkb:immune_response
cell proliferation
gene expression
cell migration
cell cycle
cytokine production
gptkbp:target gptkb:p38_inhibitors
gptkbp:bfsParent gptkb:p38_MAPK_pathway
gptkbp:bfsLayer 6
https://www.w3.org/2000/01/rdf-schema#label p38 mitogen-activated protein kinases