Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:PI3-kinase_p110_alpha
gptkb:phosphatidylinositol_4,5-bisphosphate_3-kinase_catalytic_subunit_alpha_isoform |
| gptkbp:component |
gptkb:phosphoinositide_3-kinase_(PI3K)_complex
|
| gptkbp:encodedBy |
gptkb:PIK3CA_gene
|
| gptkbp:enzymeClassification |
gptkb:EC_2.7.1.153
|
| gptkbp:function |
catalytic subunit of PI3K
|
| https://www.w3.org/2000/01/rdf-schema#label |
p110α protein
|
| gptkbp:interactsWith |
p85 regulatory subunit
|
| gptkbp:involvedIn |
cell proliferation
cell survival cell growth insulin signaling pathway |
| gptkbp:location |
gptkb:cytoplasm
gptkb:plasma_membrane |
| gptkbp:molecularWeight |
~110 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
gptkb:endometrial_cancer colorectal cancer |
| gptkbp:subunit |
gptkb:class_IA_PI3K
|
| gptkbp:bfsParent |
gptkb:PI3KCA
|
| gptkbp:bfsLayer |
6
|