Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:C23
Nsr1 (in yeast) Nucleolar protein C23 |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:virus autoimmune diseases |
| gptkbp:binds |
gptkb:gene
proteins |
| gptkbp:biologicalProcess |
signal transduction
cell cycle regulation response to stress ribosome assembly |
| gptkbp:discoveredBy |
1973
|
| gptkbp:expressedIn |
most eukaryotic cells
|
| gptkbp:foundIn |
gptkb:nucleus
gptkb:cytoplasm nucleolus |
| gptkbp:function |
cell proliferation
regulation of transcription apoptosis regulation ribosome biogenesis chromatin remodeling rRNA processing regulation of mRNA stability |
| gptkbp:gene |
gptkb:NCL
|
| https://www.w3.org/2000/01/rdf-schema#label |
nucleolin
|
| gptkbp:interactsWith |
gptkb:Bcl-2
gptkb:histone_H1 gptkb:p53 telomerase HIV-1 Rev protein nucleophosmin |
| gptkbp:locatedOnChromosome |
2q37.1
|
| gptkbp:molecularWeight |
~100 kDa
|
| gptkbp:ortholog_in_Arabidopsis |
NUC1
|
| gptkbp:orthologInMouse |
Ncl
|
| gptkbp:orthologInYeast |
Nsr1
|
| gptkbp:postTranslationalModification |
phosphorylation
methylation acetylation |
| gptkbp:structure |
contains RNA recognition motifs
contains glycine/arginine-rich domain contains acidic N-terminal domain |
| gptkbp:target |
antibodies
small molecules AS1411 (aptamer) |
| gptkbp:UniProtID |
P19338
|
| gptkbp:bfsParent |
gptkb:NPM1
|
| gptkbp:bfsLayer |
6
|