Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
cell surface receptor |
| gptkbp:alternativeSplicing |
produces multiple isoforms
|
| gptkbp:associatedWith |
angiogenesis
immune response tumor progression |
| gptkbp:binds |
gptkb:vascular_endothelial_growth_factor_(VEGF)
semaphorins |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:NRP1_gene
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
mediates cell signaling
involved in axon guidance acts as a co-receptor for VEGF |
| https://www.w3.org/2000/01/rdf-schema#label |
neuropilin-1 receptor
|
| gptkbp:interactsWith |
gptkb:VEGFR2
plexins |
| gptkbp:location |
gptkb:plasma_membrane
|
| gptkbp:molecularWeight |
~130 kDa
|
| gptkbp:role |
nervous system development
cancer metastasis cardiovascular development SARS-CoV-2 cell entry |
| gptkbp:structure |
single-pass type I membrane protein
|
| gptkbp:UniProtID |
O14786
|
| gptkbp:bfsParent |
gptkb:NRP1
|
| gptkbp:bfsLayer |
6
|