|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD304
VEGF165R
neuropilin 1
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
angiogenesis
cancer progression
axonal guidance
|
|
gptkbp:discoveredIn
|
1997
|
|
gptkbp:encodes
|
neuropilin-1 protein
|
|
gptkbp:Entrez_Gene_ID
|
8829
ENSG00000099250
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
heart
neurons
endothelial cells
|
|
gptkbp:function
|
cell migration
immune response
cell adhesion
vascular endothelial growth factor receptor activity
semaphorin receptor activity
|
|
gptkbp:GOProcess
|
nervous system development
blood vessel morphogenesis
|
|
gptkbp:HGNC_ID
|
HGNC:8004
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
NRP1 gene
|
|
gptkbp:interactsWith
|
gptkb:VEGFA
gptkb:KDR
gptkb:SEMA3A
PLXNA1
|
|
gptkbp:length
|
923 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_10
10p12.1
|
|
gptkbp:mutationAssociatedWith
|
congenital heart defects
vascular malformations
|
|
gptkbp:OMIM
|
602069
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Nrp1
|
|
gptkbp:product
|
single-pass type I membrane protein
neuropilin-1
|
|
gptkbp:receptorFor
|
gptkb:VEGF165
semaphorin 3A
|
|
gptkbp:UniProtID
|
O14786
|
|
gptkbp:bfsParent
|
gptkb:NRP1
|
|
gptkbp:bfsLayer
|
6
|