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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
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gptkb:MKK4
gptkb:JNKK1
SEK1
|
|
gptkbp:encodes
|
gptkb:Mitogen-activated_protein_kinase_kinase_4
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSMUSG00000021835
26395
|
|
gptkbp:expressedIn
|
various tissues
|
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gptkbp:function
|
protein serine/threonine kinase activity
MAP kinase kinase activity
|
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gptkbp:gene
|
Map2k4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
mouse MAP2K4
|
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gptkbp:involves
|
gptkb:MAPK_signaling_pathway
stress-activated protein kinase signaling cascade
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
|
|
gptkbp:mutationAssociatedWith
|
embryonic lethality
|
|
gptkbp:organism
|
gptkb:Mus_musculus
|
|
gptkbp:orthologIn
|
human MAP2K4
|
|
gptkbp:phosphorylates
|
MAPK14 (p38)
MAPK8 (JNK1)
MAPK9 (JNK2)
|
|
gptkbp:proteinFamily
|
gptkb:MAP_kinase_kinase_family
|
|
gptkbp:regulates
|
apoptosis
cell differentiation
cell proliferation
|
|
gptkbp:requires
|
embryonic development
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:UniProtID
|
Q9Z1S4
|
|
gptkbp:bfsParent
|
gptkb:MAP2K4
|
|
gptkbp:bfsLayer
|
8
|