|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:vitamin_A
|
|
gptkbp:approved_for_use_in
|
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:ATCCode
|
B03BB51
|
|
gptkbp:availableOn
|
gptkb:tablet
capsule
oral solution
|
|
gptkbp:CASNumber
|
31690-09-2
|
|
gptkbp:chemicalFormula
|
C20H25N7O6
|
|
gptkbp:cofactor
|
gptkb:methionine_synthase
thymidylate synthase
methylene tetrahydrofolate reductase (MTHFR)
|
|
gptkbp:combines
|
gptkb:methotrexate
anticonvulsants
antidepressants
|
|
gptkbp:contraindication
|
hypersensitivity to folate
|
|
gptkbp:form
|
folate
vitamin B9
|
|
gptkbp:foundIn
|
dietary supplements
prescription medications
|
|
gptkbp:has_chiral_center
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
levomefolic acid
|
|
gptkbp:is_a_methyl_donor
|
yes
|
|
gptkbp:is_absorbed_in
|
gptkb:small_intestine
|
|
gptkbp:is_active_form_of
|
folic acid
|
|
gptkbp:is_excreted_via
|
urine
|
|
gptkbp:is_not_affected_by
|
MTHFR polymorphism
|
|
gptkbp:is_prescription_drug
|
yes
|
|
gptkbp:is_recommended_for
|
pregnant women
patients with MTHFR mutation
|
|
gptkbp:is_water_soluble
|
yes
|
|
gptkbp:IUPACName
|
gptkb:(6S)-5-methyltetrahydrofolic_acid
|
|
gptkbp:marketedAs
|
Deplin
Metafolin
Quatrefolic
|
|
gptkbp:metabolism
|
folic acid
folinic acid
|
|
gptkbp:metabolized_from
|
folic acid
|
|
gptkbp:molecularWeight
|
459.45 g/mol
|
|
gptkbp:otherName
|
gptkb:5-MTHF
gptkb:L-methylfolate
|
|
gptkbp:requires
|
cell division
DNA synthesis
methylation reactions
|
|
gptkbp:usedFor
|
gptkb:depression
folate deficiency
hyperhomocysteinemia
|
|
gptkbp:bfsParent
|
gptkb:Methyltetrahydrofolate
|
|
gptkbp:bfsLayer
|
7
|