|
gptkbp:instanceOf
|
gptkb:chemical_compound
vitamin derivative
|
|
gptkbp:availableOn
|
gptkb:drug
dietary supplement
|
|
gptkbp:CASNumber
|
134-35-0
|
|
gptkbp:chemicalFormula
|
C20H25N7O6
|
|
gptkbp:cofactor
|
gptkb:methionine_synthase
|
|
gptkbp:crosses_the_blood-brain_barrier
|
yes
|
|
gptkbp:deficiency_can_cause
|
megaloblastic anemia
elevated homocysteine
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:form
|
folate
vitamin B9
|
|
gptkbp:foundIn
|
citrus fruits
legumes
leafy green vegetables
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
5-MTHF
|
|
gptkbp:is_affected_by_mutation_in
|
MTHFR gene
|
|
gptkbp:is_more_bioavailable_than
|
folic acid
|
|
gptkbp:is_not_stored_in
|
large amounts in the body
|
|
gptkbp:is_the_primary_biologically_active_form_of
|
folate in the human body
|
|
gptkbp:IUPACName
|
gptkb:(6S)-5-methyltetrahydrofolic_acid
|
|
gptkbp:marketedAs
|
Deplin
Metafolin
Quatrefolic
|
|
gptkbp:molecularWeight
|
459.46 g/mol
|
|
gptkbp:otherName
|
gptkb:L-methylfolate
gptkb:levomefolic_acid
5-methyltetrahydrofolate
|
|
gptkbp:produced_by_enzyme
|
methylenetetrahydrofolate reductase (MTHFR)
|
|
gptkbp:produces
|
gptkb:5,10-methylenetetrahydrofolate
|
|
gptkbp:requires
|
amino acid metabolism
DNA synthesis
methylation reactions
|
|
gptkbp:solubility
|
soluble
|
|
gptkbp:substrate
|
gptkb:methionine_synthase
|
|
gptkbp:used_in
|
prenatal vitamins
medical food products
|
|
gptkbp:usedFor
|
gptkb:depression
folate deficiency
hyperhomocysteinemia
|
|
gptkbp:bfsParent
|
gptkb:Methyltetrahydrofolate
|
|
gptkbp:bfsLayer
|
7
|