|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:vitamin_A
dietary supplement
|
|
gptkbp:administeredBy
|
capsule
oral tablet
|
|
gptkbp:approvedBy
|
gptkb:United_States
|
|
gptkbp:brand
|
Deplin
EnLyte
Metafolin
|
|
gptkbp:CASNumber
|
134-35-0
|
|
gptkbp:chemicalFormula
|
C20H25N7O6
|
|
gptkbp:chirality
|
S-enantiomer
|
|
gptkbp:contraindication
|
hypersensitivity to folate
|
|
gptkbp:crossesBloodBrainBarrier
|
true
|
|
gptkbp:foundIn
|
dietary supplements
fortified foods
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
L-methylfolate
|
|
gptkbp:involvedIn
|
one-carbon metabolism
remethylation of homocysteine to methionine
|
|
gptkbp:isActiveFormOf
|
folate
|
|
gptkbp:isBioavailableFormOf
|
folate
|
|
gptkbp:isMedicalFood
|
true
|
|
gptkbp:isomerOf
|
5-methyltetrahydrofolate
|
|
gptkbp:isPrescriptionProduct
|
true
|
|
gptkbp:IUPACName
|
gptkb:(6S)-5-methyltetrahydrofolic_acid
|
|
gptkbp:metabolism
|
folic acid
|
|
gptkbp:molecularWeight
|
459.46 g/mol
|
|
gptkbp:notRegulatedAs
|
gptkb:drug
|
|
gptkbp:pregnancyCategory
|
A
|
|
gptkbp:regulates
|
FDA (as medical food)
|
|
gptkbp:relatedTo
|
folic acid
vitamin B9
folinic acid
|
|
gptkbp:requires
|
DNA synthesis
homocysteine metabolism
methylation reactions
|
|
gptkbp:sideEffect
|
insomnia
gastrointestinal upset
irritability
|
|
gptkbp:synthesisType
|
gptkb:MTHFR_enzyme
|
|
gptkbp:usedFor
|
treatment of folate deficiency
adjunct in depression treatment
adjunct in schizophrenia treatment
|
|
gptkbp:usedIn
|
neurology
nutrition
obstetrics
psychiatry
|
|
gptkbp:waterSoluble
|
true
|
|
gptkbp:bfsParent
|
gptkb:Methyltetrahydrofolate
|
|
gptkbp:bfsLayer
|
7
|