|
gptkbp:instanceOf
|
gptkb:chemical_compound
amino acid derivative
|
|
gptkbp:CASNumber
|
343-65-7
|
|
gptkbp:chemicalFormula
|
C10H12N2O3
|
|
gptkbp:enzyme
|
gptkb:indoleamine_2,3-dioxygenase
gptkb:tryptophan_2,3-dioxygenase
|
|
gptkbp:foundIn
|
urine
cerebrospinal fluid
human blood
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
kynurenine
|
|
gptkbp:is_related_to_disorder
|
gptkb:cancer
gptkb:depression
schizophrenia
neurodegenerative diseases
autoimmune diseases
|
|
gptkbp:IUPACName
|
(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
|
|
gptkbp:ligand
|
aryl hydrocarbon receptor
|
|
gptkbp:mass
|
208.22 g/mol
|
|
gptkbp:meltingPoint
|
240°C
|
|
gptkbp:metabolism
|
tryptophan
|
|
gptkbp:pathway
|
gptkb:tryptophan_metabolism
|
|
gptkbp:predecessor
|
gptkb:3-hydroxykynurenine
gptkb:kynurenic_acid
anthranilic acid
|
|
gptkbp:produces
|
tryptophan
|
|
gptkbp:role
|
inflammation
immune regulation
neurotransmission
|
|
gptkbp:substrate
|
gptkb:kynureninase
gptkb:kynurenine_3-monooxygenase
gptkb:kynurenine_aminotransferase
|
|
gptkbp:bfsParent
|
gptkb:Magnetic_Resonance_Spectroscopy
|
|
gptkbp:bfsLayer
|
7
|