|
gptkbp:instanceOf
|
gptkb:chemical_compound
metabolite
|
|
gptkbp:actsOn
|
NMDA receptor antagonist
AMPA receptor antagonist
alpha-7 nicotinic acetylcholine receptor antagonist
|
|
gptkbp:CASNumber
|
238-38-9
|
|
gptkbp:chemicalFormula
|
C10H7NO3
|
|
gptkbp:discoveredBy
|
gptkb:Leopold_Gmelin
|
|
gptkbp:discoveredIn
|
1853
|
|
gptkbp:effect
|
implicated in schizophrenia
modulates neurotransmission
implicated in neurodegenerative diseases
implicated in cognitive dysfunction
inhibits glutamate receptors
|
|
gptkbp:foundIn
|
gptkb:human
cerebrospinal fluid
|
|
gptkbp:hasRole
|
anticonvulsant
neuroprotective agent
endogenous neuromodulator
|
|
gptkbp:heldBy
|
gptkb:carboxylic_acid
quinoline derivative
hydroxy acid
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
kynurenic acid
|
|
gptkbp:IUPACName
|
4-hydroxyquinoline-2-carboxylic acid
|
|
gptkbp:meltingPoint
|
330 °C
|
|
gptkbp:molecularWeight
|
189.17 g/mol
|
|
gptkbp:pathway
|
gptkb:tryptophan_metabolism
|
|
gptkbp:predecessor
|
gptkb:kynurenine
|
|
gptkbp:product_of_enzyme
|
gptkb:kynurenine_aminotransferase
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:bfsParent
|
gptkb:Kynurenine_pathway
gptkb:kynurenine
gptkb:xanthurenic_acid
|
|
gptkbp:bfsLayer
|
8
|