tryptophan 2,3-dioxygenase

GPTKB entity

Statements (25)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:tryptophan_pyrrolase
gptkb:TDO
tryptophan oxygenase
gptkbp:catalyzes oxidation of L-tryptophan to N-formylkynurenine
gptkbp:cofactor hemoglobin
gptkbp:discoveredBy 1950s
gptkbp:EC_number 1.13.11.11
gptkbp:foundIn liver
gptkbp:gene gptkb:TDO2
https://www.w3.org/2000/01/rdf-schema#label tryptophan 2,3-dioxygenase
gptkbp:inhibitedBy corticosteroids
tryptophan analogs
gptkbp:pathway tryptophan catabolism
gptkbp:presentIn gptkb:Bacteria
mammals
gptkbp:product N-formylkynurenine
gptkbp:regulates tryptophan levels
gptkbp:requires molecular oxygen
gptkbp:structure homotetramer
gptkbp:substrate L-tryptophan
gptkbp:bfsParent gptkb:TDO2
gptkb:tryptophan_pyrrolase
gptkb:EC_1.14.13.13
gptkbp:bfsLayer 7