Statements (24)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
CD218a (for IL-18Rα)
CD218b (for IL-18Rβ) IL-18R |
gptkbp:associatedWith |
infectious diseases
autoimmune diseases inflammatory response |
gptkbp:binds |
gptkb:interleukin-18
|
gptkbp:encodedBy |
IL18R1 gene
IL18RAP gene |
gptkbp:expressedIn |
gptkb:NK_cells
gptkb:T_cells macrophages immune cells |
gptkbp:function |
activates NF-κB pathway
induces IFN-γ production mediates IL-18 signaling |
https://www.w3.org/2000/01/rdf-schema#label |
IL-18 receptor
|
gptkbp:locatedIn |
gptkb:cell_membrane
|
gptkbp:memberOf |
interleukin-1 receptor family
|
gptkbp:subunit |
IL-18Rα
IL-18Rβ |
gptkbp:bfsParent |
gptkb:interleukin-18
|
gptkbp:bfsLayer |
8
|