Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
IGIF
interferon-gamma inducing factor |
| gptkbp:associatedWith |
gptkb:Crohn's_disease
asthma autoimmune diseases inflammatory diseases rheumatoid arthritis |
| gptkbp:discoveredBy |
gptkb:Tetsuji_Okamura
|
| gptkbp:discoveredIn |
1995
|
| gptkbp:encodes |
gptkb:interleukin-18
|
| gptkbp:Entrez_Gene_ID |
3606
ENSG00000150782 |
| gptkbp:expressedIn |
dendritic cells
macrophages epithelial cells |
| gptkbp:function |
immune response regulation
cytokine activity |
| gptkbp:HGNC_ID |
HGNC:5986
|
| gptkbp:locatedOnChromosome |
gptkb:11q23.1
|
| gptkbp:mutationAssociatedWith |
gptkb:macrophage_activation_syndrome
systemic juvenile idiopathic arthritis |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
mouse Il18 gene
|
| gptkbp:product |
gptkb:IL-18
|
| gptkbp:regulates |
inflammatory response
IFN-gamma production Th1 cell differentiation |
| gptkbp:UniProtID |
gptkb:Q14116
|
| gptkbp:bfsParent |
gptkb:interleukin-18
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
IL18 gene
|