Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
gptkb:CD11a
LFA-1 alpha chain |
gptkbp:cellSurfaceMarker |
gptkb:CD11a
|
gptkbp:component |
gptkb:LFA-1
|
gptkbp:encodedBy |
ITGAL gene
|
gptkbp:expressedIn |
gptkb:leukocytes
|
gptkbp:formsComplexWith |
gptkb:integrin_beta_2_(CD18)
|
gptkbp:foundIn |
gptkb:Homo_sapiens
|
gptkbp:function |
immune response
cell adhesion leukocyte migration |
gptkbp:gene |
gptkb:ITGAL
|
https://www.w3.org/2000/01/rdf-schema#label |
integrin alpha L (CD11a)
|
gptkbp:interactsWith |
gptkb:ICAM-1
gptkb:ICAM-2 gptkb:ICAM-3 |
gptkbp:locatedOnChromosome |
16q13
|
gptkbp:molecularWeight |
~180 kDa
|
gptkbp:role |
T cell activation
immune synapse formation lymphocyte adhesion transendothelial migration |
gptkbp:structure |
type I membrane protein
|
gptkbp:subunit |
LFA-1 (lymphocyte function-associated antigen 1)
|
gptkbp:UniProtID |
P20701
|
gptkbp:bfsParent |
gptkb:integrin_beta_2_(CD18)
|
gptkbp:bfsLayer |
7
|