gptkbp:instanceOf
|
gptkb:protein
|
gptkbp:alternativeName
|
CD102
|
gptkbp:alternativeSplicing
|
yes
|
gptkbp:associatedWith
|
gptkb:cancer
atherosclerosis
autoimmune diseases
inflammatory diseases
allergic diseases
|
gptkbp:CDAntigen
|
CD102
|
gptkbp:discoveredIn
|
1991
|
gptkbp:encodedBy
|
ICAM2 gene
|
gptkbp:Entrez_Gene_ID
|
3384
|
gptkbp:expressedIn
|
gptkb:leukocytes
platelets
endothelial cells
|
gptkbp:foundIn
|
humans
other mammals
|
gptkbp:fullName
|
Intercellular Adhesion Molecule 2
|
gptkbp:function
|
cell adhesion
leukocyte transmigration
|
gptkbp:gene
|
ICAM2
|
gptkbp:HGNC_ID
|
5346
|
https://www.w3.org/2000/01/rdf-schema#label
|
ICAM-2
|
gptkbp:interactsWith
|
gptkb:integrins
gptkb:LFA-1
|
gptkbp:locatedOnChromosome
|
17q23-q25
|
gptkbp:location
|
gptkb:cell_membrane
|
gptkbp:memberOf
|
gptkb:immunoglobulin_superfamily
|
gptkbp:molecularWeight
|
55 kDa
|
gptkbp:numberOfIgDomains
|
2
|
gptkbp:OMIM
|
147840
|
gptkbp:orthologIn
|
gptkb:dog
gptkb:lion
gptkb:livestock
gptkb:mouse
right
|
gptkbp:PDB
|
1ZXQ
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
gptkbp:relatedTo
|
gptkb:ICAM-1
gptkb:ICAM-3
ICAM-4
ICAM-5
|
gptkbp:role
|
angiogenesis
inflammation
immune response
tumor metastasis
|
gptkbp:structure
|
type I transmembrane glycoprotein
|
gptkbp:UniProtID
|
P13598
|
gptkbp:bfsParent
|
gptkb:integrin_beta_2_(CD18)
|
gptkbp:bfsLayer
|
7
|