Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
DNA repair mechanism
|
| gptkbp:alsoKnownAs |
HDR
|
| gptkbp:contrastsWith |
gptkb:non-homologous_end_joining
|
| gptkbp:firstDescribed |
1970s
|
| https://www.w3.org/2000/01/rdf-schema#label |
homology-directed repair
|
| gptkbp:importantFor |
genome stability
|
| gptkbp:involves |
gptkb:BRCA1_protein
gptkb:DNA_ligase gptkb:BRCA2_protein DNA polymerase homologous recombination Rad51 protein |
| gptkbp:isErrorFree |
true
|
| gptkbp:occurredIn |
gptkb:S_phase
G2 phase |
| gptkbp:repairs |
double-strand DNA breaks
|
| gptkbp:requires |
homologous DNA template
|
| gptkbp:studiedIn |
gptkb:yeast
mammalian cells |
| gptkbp:utilizedBy |
gptkb:CRISPR-Cas9
|
| gptkbp:utilizedIn |
genome editing
|
| gptkbp:bfsParent |
gptkb:Zinc_Finger_Nuclease
|
| gptkbp:bfsLayer |
7
|