Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
gptkb:cancer
|
| gptkbp:discoveredBy |
gptkb:Michael_Stratton
|
| gptkbp:discoveredIn |
1995
|
| gptkbp:encodedBy |
gptkb:BRCA2_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA repair
homologous recombination |
| https://www.w3.org/2000/01/rdf-schema#label |
BRCA2 protein
|
| gptkbp:interactsWith |
gptkb:RAD51_protein
|
| gptkbp:length |
3418 amino acids
|
| gptkbp:locale |
gptkb:nucleus
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_13q13.1
|
| gptkbp:molecularWeight |
384 kDa
|
| gptkbp:mutationAssociatedWith |
increased cancer risk
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Pan_troglodytes |
| gptkbp:PDB |
1MIU
|
| gptkbp:postTranslationalModification |
phosphorylation
ubiquitination |
| gptkbp:role |
tumor suppression
Fanconi anemia pathway |
| gptkbp:structure |
contains DNA-binding domain
contains BRC repeats |
| gptkbp:UniProtID |
P51587
|
| gptkbp:bfsParent |
gptkb:ENSG00000135679
gptkb:Partner_and_localizer_of_BRCA2_protein gptkb:BRCA1_protein gptkb:BRCA2 gptkb:FANCD1 |
| gptkbp:bfsLayer |
7
|