heat shock protein HSP 90-beta

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alsoKnownAs	gptkb:HSP90AB1
gptkbp:encodedBy	HSP90AB1 gene
gptkbp:Entrez_Gene_ID	3326
gptkbp:expressedIn	most tissues
gptkbp:family	gptkb:heat_shock_protein_90_family
gptkbp:function	gptkb:cellular_stress_response gptkb:molecular_chaperone protein folding stabilization of proteins
gptkbp:interactsWith	gptkb:HSP70 co-chaperones
gptkbp:involvedIn	signal transduction protein degradation apoptosis regulation cell cycle control
gptkbp:locatedOnChromosome	gptkb:chromosome_6p21
gptkbp:location	gptkb:nucleus gptkb:cytoplasm
gptkbp:molecularWeight	~90 kDa
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Drosophila_melanogaster gptkb:Rattus_norvegicus
gptkbp:PDB	5FWK
gptkbp:postTranslationalModification	phosphorylation ubiquitination acetylation
gptkbp:RefSeq	NP_001017963.2
gptkbp:requires	cell viability
gptkbp:significance	gptkb:cancer neurodegenerative diseases
gptkbp:structure	homodimer C-terminal domain N-terminal domain ATPase domain
gptkbp:target	gptkb:HSP90_inhibitors
gptkbp:UniProtID	gptkb:P08238
gptkbp:upregulatedBy	heat shock cellular stress
gptkbp:bfsParent	gptkb:6p21.1_(HSP90AB1)
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	heat shock protein HSP 90-beta