Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:associatedWith |
microsatellite instability
|
| gptkbp:discoveredIn |
1993
|
| gptkbp:encodedBy |
MSH2 gene
|
| gptkbp:Entrez_Gene_ID |
4436
ENSG00000095002 |
| gptkbp:formsComplexWith |
gptkb:hMSH6
hMSH3 |
| gptkbp:formsMutSαComplex |
gptkb:hMSH6
|
| gptkbp:formsMutSβComplex |
hMSH3
|
| gptkbp:fullName |
human MutS homolog 2
|
| gptkbp:function |
DNA mismatch repair
|
| gptkbp:gene |
gptkb:MSH2
|
| https://www.w3.org/2000/01/rdf-schema#label |
hMSH2
|
| gptkbp:interactsWith |
gptkb:MLH1
gptkb:PMS2 gptkb:EXO1 |
| gptkbp:length |
934 amino acids
|
| gptkbp:locatedOnChromosome |
chromosome 2p21
|
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:molecularWeight |
104 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Lynch_syndrome
gptkb:hereditary_nonpolyposis_colorectal_cancer |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Msh2
|
| gptkbp:PDB |
2O8B
|
| gptkbp:RefSeq |
NP_000242
|
| gptkbp:reviewedBy |
GeneCards:MSH2
HGNC:7325 OMIM:609309 |
| gptkbp:UniProtID |
P43246
|
| gptkbp:bfsParent |
gptkb:MSH2
|
| gptkbp:bfsLayer |
6
|