Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
RNA molecule
|
| gptkbp:alternativeName |
gptkb:single_guide_RNA_(sgRNA)
|
| gptkbp:binds |
gptkb:Cas9_protein
target DNA |
| gptkbp:composedOf |
gptkb:crRNA
gptkb:tracrRNA |
| gptkbp:designedFor |
match target DNA sequence
|
| gptkbp:enables |
site-specific DNA cleavage
|
| gptkbp:function |
guides Cas9 to target DNA sequence
|
| https://www.w3.org/2000/01/rdf-schema#label |
guide RNA (gRNA)
|
| gptkbp:length |
about 100 nucleotides
|
| gptkbp:origin |
bacterial adaptive immune system
|
| gptkbp:requires |
gptkb:CRISPR_activation_(CRISPRa)
gptkb:CRISPR_interference_(CRISPRi) |
| gptkbp:used_in |
gptkb:CRISPR-Cas9_system
genome editing base editing prime editing gene activation gene knockout gene repression |
| gptkbp:bfsParent |
gptkb:CRISPR-Cas9_gene_editing_technology
|
| gptkbp:bfsLayer |
5
|