CRISPR-Cas9 gene editing technology
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:biotechnology
gene editing technology |
| gptkbp:canBe |
gene therapy
disease modeling functional genomics crop improvement |
| gptkbp:cause |
off-target effects
|
| gptkbp:discoveredBy |
gptkb:Emmanuelle_Charpentier
gptkb:Jennifer_Doudna |
| gptkbp:enables |
gene knockout
gene correction gene insertion targeted genome editing |
| gptkbp:firstPublished |
2012
|
| gptkbp:hasApplication |
cancer research
personalized medicine plant breeding synthetic biology vaccine development diagnostics pharmaceutical development gene regulation animal model creation epigenome editing antimicrobial resistance studies bioproduction gene function studies genetic disease treatment livestock improvement microbial engineering viral disease resistance xenotransplantation |
| https://www.w3.org/2000/01/rdf-schema#label |
CRISPR-Cas9 gene editing technology
|
| gptkbp:limitation |
mosaicism
immune response delivery challenges |
| gptkbp:originatedIn |
bacterial immune system
|
| gptkbp:regulates |
bioethics guidelines
|
| gptkbp:relatedTo |
gptkb:gene_drive
gptkb:CRISPR gptkb:Cas9_protein genome editing |
| gptkbp:subject |
gptkb:Nobel_Prize_in_Chemistry_2020
|
| gptkbp:used_in |
gptkb:medicine
agriculture biomedical research |
| gptkbp:uses |
gptkb:CRISPR-associated_protein_9_(Cas9)
gptkb:guide_RNA_(gRNA) |
| gptkbp:bfsParent |
gptkb:Emmanuelle_Charpentier
|
| gptkbp:bfsLayer |
4
|