Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:ENaC
|
| gptkbp:composedOf |
alpha subunit
beta subunit gamma subunit delta subunit |
| gptkbp:encodedBy |
SCNN1A
SCNN1B SCNN1D SCNN1G |
| gptkbp:foundIn |
gptkb:cancer
gptkb:kidney colon sweat gland |
| gptkbp:function |
sodium ion transport
|
| https://www.w3.org/2000/01/rdf-schema#label |
epithelial sodium channel
|
| gptkbp:inhibitedBy |
gptkb:triamterene
gptkb:amiloride |
| gptkbp:locale |
apical membrane of epithelial cells
|
| gptkbp:memberOf |
ENaC/DEG family
|
| gptkbp:mutationAssociatedWith |
gptkb:Liddle_syndrome
pseudohypoaldosteronism type 1 |
| gptkbp:permeableTo |
K+
Na+ |
| gptkbp:regulates |
gptkb:aldosterone
sodium reabsorption |
| gptkbp:role |
fluid balance
blood pressure regulation electrolyte homeostasis |
| gptkbp:structure |
heterotrimeric
|
| gptkbp:bfsParent |
gptkb:Liddle_syndrome
|
| gptkbp:bfsLayer |
8
|