Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cell surface receptor
lymphocyte |
| gptkbp:activatedBy |
gptkb:interleukin-2
antigen-presenting cell |
| gptkbp:alsoKnownAs |
gptkb:CTL
gptkb:CD8+_T_cell killer T cell |
| gptkbp:developedBy |
thymocyte
|
| gptkbp:expressedIn |
gptkb:T_cell_receptor_(TCR)
|
| gptkbp:firstDescribed |
1970s
|
| gptkbp:foundIn |
blood
lymph nodes spleen |
| gptkbp:function |
kills damaged cells
kills virus-infected cells kills tumor cells |
| https://www.w3.org/2000/01/rdf-schema#label |
cytotoxic T cell (CD8+)
|
| gptkbp:inducedBy |
apoptosis in target cells
|
| gptkbp:involvedIn |
immunotherapy
autoimmune diseases immune surveillance transplant rejection |
| gptkbp:marking |
gptkb:CD8
|
| gptkbp:partOf |
gptkb:adaptive_immune_system
|
| gptkbp:recognizedBy |
antigen presented by MHC class I
|
| gptkbp:secretes |
gptkb:TNF-alpha
gptkb:IFN-gamma gptkb:granzymes gptkb:perforin granulysin |
| gptkbp:bfsParent |
gptkb:T-cells
|
| gptkbp:bfsLayer |
6
|