cytochrome P450 family 2 subfamily C member 19

URI: https://gptkb.org/entity/cytochrome_P450_family_2_subfamily_C_member_19
GPTKB entity
Statements (39)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:CYP2C19
P450IIC19
S-mephenytoin 4'-hydroxylase
gptkbp:associatedWith gptkb:adverse_drug_reaction
poor metabolizer phenotype
gptkbp:catalyzes drug metabolism
xenobiotic metabolism
hydroxylation reactions
gptkbp:encodedBy gptkb:CYP2C19_gene
gptkbp:Entrez_Gene_ID 1557
gptkbp:expressedIn gptkb:small_intestine
liver
gptkbp:gene gptkb:CYP2C19
gptkbp:hasPolymorphism gptkb:CYP2C19*17
gptkb:CYP2C19*2
gptkb:CYP2C19*3
gptkbp:HGNC_ID 2621
gptkbp:involves metabolism of antidepressants
metabolism of antiepileptic drugs
metabolism of proton pump inhibitors
metabolism of clopidogrel
gptkbp:locatedIn gptkb:endoplasmic_reticulum
gptkbp:locatedOnChromosome chromosome 10q23.33
gptkbp:member gptkb:cytochrome_P450_superfamily
gptkbp:OMIM 124020
gptkbp:relatedTo pharmacogenomics
gptkbp:UniProtID gptkb:P33261
gptkbp:bfsParent gptkb:CYP2C19
gptkb:HGNC:2197
gptkb:ENSG00000106366
gptkb:ENSG00000110330
gptkb:HGNC:2591
gptkb:HGNC:2211
gptkb:ENSG00000140992
gptkb:ENSG00000109061
gptkbp:bfsLayer 8
https://www.w3.org/2000/01/rdf-schema#label cytochrome P450 family 2 subfamily C member 19
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