Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
CYP2C19 allele
|
| gptkbp:affects_drug_metabolism |
gptkb:proton_pump_inhibitors
gptkb:omeprazole gptkb:clopidogrel |
| gptkbp:associated_with_phenotype |
ultrarapid metabolizer
|
| gptkbp:effect |
increased enzyme activity
|
| gptkbp:found_in_population |
gptkb:Asian
African European |
| gptkbp:has_nucleotide_change |
-806C>T
|
| gptkbp:has_rsID |
rs12248560
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP2C19*17
|
| gptkbp:locatedOnChromosome |
10q23.33
|
| gptkbp:significance |
may require dose adjustment of CYP2C19 substrates
|
| gptkbp:variant |
gptkb:CYP2C19
|
| gptkbp:bfsParent |
gptkb:CYP2C19
|
| gptkbp:bfsLayer |
6
|