Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological signaling pathway
|
| gptkbp:activatedBy |
Hedgehog ligand
|
| gptkbp:associatedWith |
gptkb:cancer
birth defects |
| gptkbp:firstDescribed |
gptkb:Drosophila_melanogaster
|
| gptkbp:foundIn |
animals
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hedgehog signaling
|
| gptkbp:importantFor |
organogenesis
limb development neural tube patterning |
| gptkbp:inhibitedBy |
gptkb:cyclopamine
|
| gptkbp:involves |
gptkb:Patched_receptor
Gli transcription factors Hedgehog proteins Smoothened protein |
| gptkbp:malfunctionLeadsTo |
gptkb:medulloblastoma
gptkb:holoprosencephaly basal cell carcinoma |
| gptkbp:regulates |
cell differentiation
embryonic development tissue patterning |
| gptkbp:studiedIn |
cancer research
developmental biology |
| gptkbp:subspecies |
Desert Hedgehog pathway
Indian Hedgehog pathway Sonic Hedgehog pathway |
| gptkbp:bfsParent |
gptkb:PTCH1
|
| gptkbp:bfsLayer |
7
|