| 
                                    
                                        gptkbp:instanceOf
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:cancer
                                        
                                         
                                    
                                        
                                            gptkb:disease
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:affects
                                    
                                 | 
                                
                                    
                                        
                                            
                                            colon
                                        
                                        
                                         
                                    
                                        
                                            
                                            rectum
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:associatedWith
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:KRAS_mutation
                                        
                                         
                                    
                                        
                                            gptkb:Lynch_syndrome
                                        
                                         
                                    
                                        
                                            gptkb:familial_adenomatous_polyposis
                                        
                                         
                                    
                                        
                                            
                                            APC gene mutation
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:canMetastasizeTo
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:cancer
                                        
                                         
                                    
                                        
                                            
                                            liver
                                        
                                        
                                         
                                    
                                        
                                            
                                            peritoneum
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:diagnosedBy
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:CT_scan
                                        
                                         
                                    
                                        
                                            
                                            biopsy
                                        
                                        
                                         
                                    
                                        
                                            
                                            colonoscopy
                                        
                                        
                                         
                                    
                                        
                                            
                                            fecal occult blood test
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:hasEpidemiology
                                    
                                 | 
                                
                                    
                                        
                                            
                                            common in developed countries
                                        
                                        
                                         
                                    
                                        
                                            
                                            second leading cause of cancer death
                                        
                                        
                                         
                                    
                                        
                                            
                                            third most common cancer worldwide
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:hasScreeningTest
                                    
                                 | 
                                
                                    
                                        
                                            
                                            colonoscopy
                                        
                                        
                                         
                                    
                                        
                                            
                                            sigmoidoscopy
                                        
                                        
                                         
                                    
                                        
                                            
                                            fecal immunochemical test
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:ICD-10_code
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:C18
                                        
                                         
                                    
                                        
                                            
                                            C20
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:pathology
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:cancer
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prevention
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:physical_activity
                                        
                                         
                                    
                                        
                                            
                                            limiting alcohol
                                        
                                        
                                         
                                    
                                        
                                            
                                            healthy diet
                                        
                                        
                                         
                                    
                                        
                                            
                                            screening
                                        
                                        
                                         
                                    
                                        
                                            
                                            avoiding smoking
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:prognosis
                                    
                                 | 
                                
                                    
                                        
                                            
                                            depends on stage
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:riskFactor
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:inflammatory_bowel_disease
                                        
                                         
                                    
                                        
                                            
                                            age
                                        
                                        
                                         
                                    
                                        
                                            
                                            family history
                                        
                                        
                                         
                                    
                                        
                                            
                                            alcohol consumption
                                        
                                        
                                         
                                    
                                        
                                            
                                            obesity
                                        
                                        
                                         
                                    
                                        
                                            
                                            smoking
                                        
                                        
                                         
                                    
                                        
                                            
                                            diet high in red meat
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:symptom
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:anemia
                                        
                                         
                                    
                                        
                                            
                                            abdominal pain
                                        
                                        
                                         
                                    
                                        
                                            
                                            weight loss
                                        
                                        
                                         
                                    
                                        
                                            
                                            rectal bleeding
                                        
                                        
                                         
                                    
                                        
                                            
                                            change in bowel habits
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:synonym
                                    
                                 | 
                                
                                    
                                        
                                            
                                            colorectal cancer
                                        
                                        
                                         
                                    
                                        
                                            
                                            colon cancer
                                        
                                        
                                         
                                    
                                        
                                            
                                            rectal cancer
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:treatment
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:radiation_therapy
                                        
                                         
                                    
                                        
                                            gptkb:targeted_therapy
                                        
                                         
                                    
                                        
                                            
                                            surgery
                                        
                                        
                                         
                                    
                                        
                                            
                                            chemotherapy
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsParent
                                    
                                 | 
                                
                                    
                                        
                                            gptkb:P15018
                                        
                                         
                                    
                                        
                                            gptkb:cytokeratin_7
                                        
                                         
                                    
                                        
                                            gptkb:CK20
                                        
                                         
                                    
                                        
                                            gptkb:CK7
                                        
                                         
                                    
                                        
                                            gptkb:TTF-1
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        gptkbp:bfsLayer
                                    
                                 | 
                                
                                    
                                        
                                            
                                            8
                                        
                                        
                                         
                                    
                                 | 
                            
                        
                            
                                | 
                                    
                                        https://www.w3.org/2000/01/rdf-schema#label
                                    
                                 | 
                                
                                    
                                        
                                            
                                            colorectal carcinoma
                                        
                                        
                                         
                                    
                                 |