Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
|
| gptkbp:affects |
gptkb:KRAS_gene
|
| gptkbp:associatedWith |
gptkb:cancer
colorectal cancer pancreatic cancer |
| gptkbp:cause |
constitutive activation of KRAS protein
abnormal cell growth |
| gptkbp:detects |
genetic testing
|
| gptkbp:firstDescribed |
1980s
|
| gptkbp:frequencyInColorectalCancer |
~40%
|
| gptkbp:grapeVariety |
gptkb:G12V
gptkb:G13D G12D |
| https://www.w3.org/2000/01/rdf-schema#label |
KRAS mutation
|
| gptkbp:impact |
response to EGFR inhibitors
|
| gptkbp:type |
oncogenic mutation
|
| gptkbp:bfsParent |
gptkb:cancer
|
| gptkbp:bfsLayer |
4
|