|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:apoptosome
|
|
gptkbp:alternativeSplicing
|
produces multiple isoforms
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:cancer
myocardial infarction
|
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gptkbp:biologicalProcess
|
apoptotic process
cysteine-type endopeptidase activity
|
|
gptkbp:cellularComponent
|
cytosol
mitochondrion
|
|
gptkbp:cleavage
|
caspase-3 protein
caspase-7 protein
|
|
gptkbp:discoveredBy
|
1997
|
|
gptkbp:EC_number
|
3.4.22.62
|
|
gptkbp:encodedBy
|
CASP9 gene
|
|
gptkbp:function
|
initiator caspase in apoptosis
|
|
gptkbp:GOID
|
GO:0004197
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
caspase-9 protein
|
|
gptkbp:inhibitedBy
|
BIRC2 protein
XIAP protein
|
|
gptkbp:locatedOnChromosome
|
chromosome 1p36.21
|
|
gptkbp:molecularWeight
|
46 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
Mus musculus caspase-9
Rattus norvegicus caspase-9
|
|
gptkbp:PDB
|
1JXQ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
|
|
gptkbp:structure
|
contains CARD domain
|
|
gptkbp:UniProtID
|
gptkb:P55211
|
|
gptkbp:bfsParent
|
gptkb:CASP9
|
|
gptkbp:bfsLayer
|
8
|