cannabinoid receptor type 1 (CB1)

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:G_protein-coupled_receptor
gptkbp:binds	gptkb:endocannabinoids gptkb:anandamide gptkb:2-arachidonoylglycerol_(2-AG) gptkb:tetrahydrocannabinol_(THC) synthetic cannabinoids
gptkbp:biologicalProcess	signal transduction inhibition of neurotransmitter release
gptkbp:discoveredIn	1990
gptkbp:encodedBy	gptkb:CNR1_gene
gptkbp:enemyOf	gptkb:THC gptkb:2-AG gptkb:SR141716A gptkb:anandamide gptkb:rimonabant
gptkbp:expressedIn	neurons astrocytes presynaptic terminals
gptkbp:foundIn	gptkb:skeletal_muscle brain gastrointestinal tract central nervous system liver adipose tissue peripheral nervous system
gptkbp:HGNC_ID	2159
https://www.w3.org/2000/01/rdf-schema#label	cannabinoid receptor type 1 (CB1)
gptkbp:involvedIn	gptkb:endocannabinoid_system
gptkbp:locatedOn	gptkb:chromosome_6
gptkbp:OMIM	114610
gptkbp:otherName	gptkb:CB1_receptor gptkb:CNR1 gptkb:central_cannabinoid_receptor
gptkbp:PDB	gptkb:5U09 gptkb:6KPC gptkb:6KPF gptkb:6N4B gptkb:6N4C 5TGZ 6KQI
gptkbp:regulates	memory appetite mood pain sensation reward pathways motor function
gptkbp:relatedTo	gptkb:cannabinoid_receptor_type_2_(CB2)
gptkbp:structure	seven transmembrane domains
gptkbp:UniProtID	gptkb:P21554
gptkbp:bfsParent	gptkb:SR141716A gptkb:rimonabant
gptkbp:bfsLayer	7