c-Jun N-terminal kinase 2

URI: https://gptkb.org/entity/c-Jun_N-terminal_kinase_2
GPTKB entity
Statements (35)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:MAPK9
gptkb:JNK2
gptkb:Mitogen-activated_protein_kinase_9
gptkbp:EC_number 2.7.11.24
gptkbp:encodedBy gptkb:MAPK9_gene
gptkbp:expressedIn various tissues
gptkbp:function regulates apoptosis
regulates gene expression
involved in stress response
phosphorylates c-Jun
gptkbp:GO_term gptkb:GO:0004707
https://www.w3.org/2000/01/rdf-schema#label c-Jun N-terminal kinase 2
gptkbp:involvedIn gptkb:MAPK_signaling_pathway
apoptosis regulation
inflammatory response
cellular response to stress
gptkbp:locatedOnChromosome gptkb:chromosome_5q35.3
gptkbp:memberOf gptkb:MAP_kinase_family
JNK family
gptkbp:molecularWeight ~48 kDa
gptkbp:OMIM 602896
gptkbp:organism gptkb:Homo_sapiens
gptkbp:PDB 3E7O
gptkbp:phosphorylates gptkb:ATF2
gptkb:Elk-1
gptkb:c-Jun
gptkbp:regulates activated by phosphorylation
activated by cytokines
activated by environmental stress
gptkbp:structure serine/threonine kinase
gptkbp:UniProtID P45984
gptkbp:bfsParent gptkb:MAPK9
gptkbp:bfsLayer 7