bZIP transcription factors

GPTKB entity

Statements (40)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName basic leucine zipper transcription factors
gptkbp:binds specific DNA sequences
gptkbp:dimerization leucine zipper
gptkbp:discoveredIn 1980s
gptkbp:domain basic leucine zipper domain
gptkbp:example gptkb:CREB
gptkb:c-Jun
gptkb:ATF
gptkb:c-Fos
gptkb:AP-1
gptkbp:form heterodimers
homodimers
gptkbp:foundIn animals
fungi
plants
eukaryotes
gptkbp:function transcription regulation
DNA binding
gptkbp:GO_term GO:0003700
https://www.w3.org/2000/01/rdf-schema#label bZIP transcription factors
gptkbp:InterPro IPR004827
gptkbp:involvedIn cell differentiation
development
metabolism
immune response
stress response
gptkbp:motif N-X7-L-X6-L-X6-L
gptkbp:mutationAssociatedWith gptkb:cancer
metabolic disorders
disease association
gptkbp:proteinFamily PF00170
gptkbp:regulates signal transduction
gene expression
phosphorylation
protein-protein interaction
gptkbp:structure basic region for DNA binding
leucine zipper for dimerization
gptkbp:bfsParent gptkb:ATF_family
gptkbp:bfsLayer 7