Statements (40)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alternativeName |
basic leucine zipper transcription factors
|
gptkbp:binds |
specific DNA sequences
|
gptkbp:dimerization |
leucine zipper
|
gptkbp:discoveredIn |
1980s
|
gptkbp:domain |
basic leucine zipper domain
|
gptkbp:example |
gptkb:CREB
gptkb:c-Jun gptkb:ATF gptkb:c-Fos gptkb:AP-1 |
gptkbp:form |
heterodimers
homodimers |
gptkbp:foundIn |
animals
fungi plants eukaryotes |
gptkbp:function |
transcription regulation
DNA binding |
gptkbp:GO_term |
GO:0003700
|
https://www.w3.org/2000/01/rdf-schema#label |
bZIP transcription factors
|
gptkbp:InterPro |
IPR004827
|
gptkbp:involvedIn |
cell differentiation
development metabolism immune response stress response |
gptkbp:motif |
N-X7-L-X6-L-X6-L
|
gptkbp:mutationAssociatedWith |
gptkb:cancer
metabolic disorders disease association |
gptkbp:proteinFamily |
PF00170
|
gptkbp:regulates |
signal transduction
gene expression phosphorylation protein-protein interaction |
gptkbp:structure |
basic region for DNA binding
leucine zipper for dimerization |
gptkbp:bfsParent |
gptkb:ATF_family
|
gptkbp:bfsLayer |
7
|