Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:category |
neurotrophin
|
| gptkbp:discoveredBy |
gptkb:Rita_Levi-Montalcini
gptkb:Stanley_Cohen |
| gptkbp:discoveredIn |
1950s
|
| gptkbp:encodedBy |
NGF gene
|
| gptkbp:foundIn |
humans
mammals |
| gptkbp:fullName |
alpha Nerve Growth Factor
|
| gptkbp:function |
promotes growth and survival of neurons
nerve growth factor activity |
| gptkbp:gene |
gptkb:NGF
|
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-NGF
|
| gptkbp:location |
extracellular space
|
| gptkbp:medicalUse |
studied for neurodegenerative diseases
|
| gptkbp:molecularWeight |
~13 kDa
|
| gptkbp:recipient |
gptkb:TrkA
gptkb:p75NTR |
| gptkbp:relatedTo |
gptkb:beta-NGF
gptkb:gamma-NGF |
| gptkbp:role |
regulates neuronal differentiation
involved in pain signaling regulates neuronal maintenance |
| gptkbp:sequence |
polypeptide
|
| gptkbp:structure |
homodimer
heterodimer with beta-NGF |
| gptkbp:UniProtID |
gptkb:P01138
|
| gptkbp:bfsParent |
gptkb:rat_NGF
|
| gptkbp:bfsLayer |
8
|