Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:activities |
reduces sebum production
inhibits sebaceous gland activity |
| gptkbp:appointed_by |
oral capsule
|
| gptkbp:approves |
gptkb:1982
gptkb:FDA |
| gptkbp:associated_with |
teratogenic effects
|
| gptkbp:brand |
Accutane
Roaccutane Claravis Isotretinoin Teva |
| gptkbp:caused_by |
fatigue
allergic reactions headaches mood swings psychological effects bone density loss birth defects gastrointestinal issues vision changes hearing changes |
| gptkbp:contraindication |
pregnancy
|
| gptkbp:discovered_by |
1970s
|
| gptkbp:dosage_form |
gptkb:beer
0.5 to 2 mg/kg/day |
| gptkbp:duration |
15 to 20 weeks
|
| https://www.w3.org/2000/01/rdf-schema#label |
isotretinoin
|
| gptkbp:ingredients |
C20 H28 N2 O2
|
| gptkbp:interacts_with |
gptkb:physicist
certain antibiotics anticonvulsants certain antifungals certain antidepressants tetracyclines certain anti-inflammatory drugs certain blood thinners progestin-only contraceptives vitamin A supplements |
| gptkbp:is_available_in |
gptkb:various_countries
|
| gptkbp:is_available_on |
generic medication
|
| gptkbp:is_monitored_by |
liver function
lipid levels |
| gptkbp:is_used_by |
dermatologists
|
| gptkbp:is_used_for |
acne
|
| gptkbp:metabolism |
liver
|
| gptkbp:related_to |
vitamin A
|
| gptkbp:requires |
i PLEDGE program
|
| gptkbp:rounds |
kidneys
|
| gptkbp:side_effect |
muscle pain
dry skin nosebleeds chapped lips |
| gptkbp:suitable_for |
patients with liver disease
patients with depression patients with high cholesterol |
| gptkbp:bfsParent |
gptkb:Retin-A
|
| gptkbp:bfsLayer |
7
|