Statements (35)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:associatedWith |
gptkb:cancer
developmental disorders |
gptkbp:foundIn |
animals
humans |
gptkbp:function |
binds Wnt proteins
activates Wnt signaling pathway |
https://www.w3.org/2000/01/rdf-schema#label |
Wnt signaling receptor
|
gptkbp:interactsWith |
gptkb:Dishevelled_protein
Wnt ligand |
gptkbp:involvedIn |
canonical Wnt pathway
non-canonical Wnt pathway |
gptkbp:location |
gptkb:cell_membrane
|
gptkbp:memberOf |
gptkb:Frizzled_family
gptkb:LRP_family |
gptkbp:proteinFamily |
gptkb:FZD1
gptkb:FZD10 gptkb:FZD2 gptkb:FZD3 gptkb:FZD4 gptkb:FZD5 gptkb:FZD6 gptkb:FZD7 gptkb:FZD8 gptkb:FZD9 gptkb:LRP5 gptkb:LRP6 |
gptkbp:role |
cell differentiation
cell proliferation embryonic development stem cell maintenance |
gptkbp:type |
gptkb:G_protein-coupled_receptor
single-pass transmembrane protein |
gptkbp:bfsParent |
gptkb:FZD5
|
gptkbp:bfsLayer |
8
|