Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:associatedWith |
bone density regulation
|
| gptkbp:discoveredIn |
1998
|
| gptkbp:encodes |
gptkb:LRP5_protein
|
| gptkbp:Entrez_Gene_ID |
4041
|
| gptkbp:expressedIn |
retina
bone tissue |
| gptkbp:fullName |
gptkb:Low-density_lipoprotein_receptor-related_protein_5
|
| gptkbp:function |
co-receptor in Wnt signaling pathway
|
| gptkbp:HGNC_ID |
HGNC:6697
|
| https://www.w3.org/2000/01/rdf-schema#label |
LRP5
|
| gptkbp:interactsWith |
gptkb:Frizzled_receptors
gptkb:Wnt_proteins |
| gptkbp:locatedOnChromosome |
gptkb:11q13.2
chromosome 11 |
| gptkbp:mutationAssociatedWith |
gptkb:bone
gptkb:familial_exudative_vitreoretinopathy gptkb:high_bone_mass_syndrome |
| gptkbp:OMIM |
603506
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologInMouse |
gptkb:Lrp5
|
| gptkbp:product |
single-pass type I membrane protein
|
| gptkbp:relatedTo |
gptkb:LRP6
|
| gptkbp:UniProtID |
O75197
|
| gptkbp:bfsParent |
gptkb:Frizzled/LRP5/6_receptor_complex
gptkb:LDL_receptor_class_A_domain gptkb:Wnt_proteins gptkb:DKK1 gptkb:LRP5/6 |
| gptkbp:bfsLayer |
7
|