|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:INT1
gptkb:Proto-oncogene_Wnt-1
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:Wnt_signaling_pathway
bone fragility
|
|
gptkbp:discoveredBy
|
gptkb:Harald_Varmus
|
|
gptkbp:encodes
|
gptkb:Wnt-1_protein
|
|
gptkbp:Entrez_Gene_ID
|
7471
ENSG00000125084
GC12P049222
|
|
gptkbp:expressedIn
|
brain
embryonic tissues
|
|
gptkbp:firstDescribed
|
1982
|
|
gptkbp:function
|
signaling molecule
regulation of cell proliferation
regulation of cell migration
|
|
gptkbp:geneType
|
protein coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
12782
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
WNT1 (human gene)
|
|
gptkbp:interactsWith
|
gptkb:Frizzled_receptors
gptkb:LRP5/6
|
|
gptkbp:involvedIn
|
embryonic development
cell fate determination
neural tube development
|
|
gptkbp:length
|
6 exons
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12
12q13.12
|
|
gptkbp:mutationAssociatedWith
|
osteogenesis imperfecta
early-onset osteoporosis
|
|
gptkbp:OMIM
|
164820
|
|
gptkbp:orthologIn
|
gptkb:Wnt1_(mouse_gene)
|
|
gptkbp:proteinFamily
|
gptkb:Wnt_family
|
|
gptkbp:regulates
|
beta-catenin signaling
|
|
gptkbp:UniProtID
|
P04628
|
|
gptkbp:bfsParent
|
gptkb:Wingless_(Drosophila_gene)
|
|
gptkbp:bfsLayer
|
7
|