Valosin-containing protein

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alternativeName	gptkb:CDC48_homolog gptkb:Tera gptkb:p97
gptkbp:associatedWith	gptkb:multisystem_proteinopathy amyotrophic lateral sclerosis inclusion body myopathy with Paget disease of bone and frontotemporal dementia
gptkbp:biologicalProcess	ATP binding protein binding ubiquitin binding
gptkbp:discoveredBy	1994
gptkbp:encodedBy	gptkb:VCP_gene
gptkbp:Entrez_Gene_ID	7415 ENSG00000165280
gptkbp:family	gptkb:AAA+_ATPase_family
gptkbp:function	protein degradation ubiquitin-dependent protein catabolic process ATPase activity
gptkbp:interactsWith	gptkb:HDAC6 gptkb:PLAA gptkb:SPATA2 gptkb:FAF1 gptkb:UBXD1 gptkb:YOD1 gptkb:Derlin-1 gptkb:NPL4 gptkb:SVIP gptkb:UFD1L gptkb:atlastin-1 p47
gptkbp:involves	DNA repair cell cycle regulation autophagy membrane fusion endoplasmic reticulum-associated degradation
gptkbp:length	806
gptkbp:locatedOnChromosome	gptkb:chromosome_9p13.3
gptkbp:location	gptkb:endoplasmic_reticulum gptkb:nucleus gptkb:cytoplasm
gptkbp:molecularWeight	89 kDa
gptkbp:OMIM	601023
gptkbp:organism	gptkb:Homo_sapiens
gptkbp:orthologIn	CDC48 (yeast) TER94 (Drosophila)
gptkbp:PDB	gptkb:5FTK
gptkbp:postTranslationalModification	phosphorylation ubiquitination
gptkbp:RefSeq	NM_007126
gptkbp:structure	hexamer
gptkbp:symbol	gptkb:VCP
gptkbp:UniProtID	gptkb:P55072
gptkbp:bfsParent	gptkb:VCP
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Valosin-containing protein