|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alias
|
Plasmalemmal porin
Porin-1
hVDAC1
|
|
gptkbp:alternativeName
|
Mitochondrial porin 1
Porin 31HL
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease
gptkb:cancer
|
|
gptkbp:discoveredBy
|
S. Benz et al.
|
|
gptkbp:discoveredIn
|
1980
|
|
gptkbp:encodedBy
|
VDAC1 gene
|
|
gptkbp:Entrez_Gene_ID
|
7416
ENSG00000213585
|
|
gptkbp:expressedIn
|
ubiquitous
|
|
gptkbp:fullName
|
Voltage-dependent anion-selective channel protein 1
|
|
gptkbp:function
|
involved in apoptosis
regulates the entry and exit of metabolites
forms a channel through the mitochondrial outer membrane
|
|
gptkbp:gene
|
gptkb:VDAC1
|
|
gptkbp:HGNC_ID
|
12652
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
VDAC1
|
|
gptkbp:interactsWith
|
gptkb:Hexokinase
gptkb:BCL2
ANT (adenine nucleotide translocator)
|
|
gptkbp:length
|
283
|
|
gptkbp:locatedOnChromosome
|
5q31.1
|
|
gptkbp:location
|
outer mitochondrial membrane
|
|
gptkbp:molecularWeight
|
~30 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Saccharomyces_cerevisiae
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
apoptosis
calcium signaling
mitochondrial metabolism
|
|
gptkbp:PDB
|
2JK4
3EMN
4C69
|
|
gptkbp:postTranslationalModification
|
phosphorylation
ubiquitination
acetylation
|
|
gptkbp:RefSeq
|
NM_003374
|
|
gptkbp:structure
|
beta-barrel
|
|
gptkbp:subcellularLocation
|
mitochondrion outer membrane
|
|
gptkbp:UniProtID
|
P21796
|
|
gptkbp:bfsParent
|
gptkb:PARK2_gene
|
|
gptkbp:bfsLayer
|
7
|