|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:ULK1
ATG1 homolog
Unc-51 homolog 1
|
|
gptkbp:component
|
ULK1 complex
|
|
gptkbp:discoveredBy
|
gptkb:Noboru_Mizushima
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodedBy
|
ULK1 gene
|
|
gptkbp:Entrez_Gene_ID
|
8408
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.1
|
|
gptkbp:function
|
serine/threonine-protein kinase activity
autophagy regulation
|
|
gptkbp:HGNC_ID
|
12558
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Unc-51-like kinase 1
|
|
gptkbp:inhibitedBy
|
gptkb:mTORC1
|
|
gptkbp:interactsWith
|
gptkb:ATG101
gptkb:ATG13
gptkb:FIP200
|
|
gptkbp:involvedIn
|
autophagy initiation
cellular response to starvation
|
|
gptkbp:length
|
1051 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:12q24.1
|
|
gptkbp:location
|
gptkb:cytoplasm
pre-autophagosomal structure
|
|
gptkbp:molecularWeight
|
112 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
C. elegans UNC-51
|
|
gptkbp:PDB
|
gptkb:4WNP
|
|
gptkbp:phosphorylates
|
gptkb:AMPK
|
|
gptkbp:product
|
ULK1 gene
|
|
gptkbp:UniProtID
|
gptkb:O75385
|
|
gptkbp:bfsParent
|
gptkb:ULK1
|
|
gptkbp:bfsLayer
|
7
|