nicotinamide adenine dinucleotide (NAD+)
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:coenzyme
|
| gptkbp:abbreviation |
NAD+
|
| gptkbp:biosynthesized_from |
gptkb:nicotinic_acid
tryptophan nicotinamide |
| gptkbp:charge |
positive
|
| gptkbp:chemicalFormula |
C21H27N7O14P2
|
| gptkbp:component |
adenine
ribose nicotinamide phosphate group |
| gptkbp:discoveredBy |
gptkb:Arthur_Harden
William John Young |
| gptkbp:discoveredIn |
1906
|
| gptkbp:foundIn |
all living cells
|
| gptkbp:function |
gptkb:electron_capture
redox reactions substrate for enzymes |
| gptkbp:involves |
oxidative phosphorylation
glycolysis cellular respiration citric acid cycle |
| gptkbp:IUPACName |
β-Nicotinamide adenine dinucleotide
|
| gptkbp:metabolism |
gptkb:signaling_molecule
gptkb:immune_response apoptosis aging DNA repair mitochondrial function inflammation gene expression regulation oxidative stress response energy transfer cell death neuroprotection circadian rhythm caloric restriction response accepts electrons donates electrons |
| gptkbp:molecularWeight |
663.43 g/mol
|
| gptkbp:oxidized_form |
NAD+
|
| gptkbp:predecessor |
niacin (vitamin B3)
|
| gptkbp:reduces |
gptkb:NADH
|
| gptkbp:used_by_enzyme |
sirtuins
dehydrogenase poly(ADP-ribose) polymerase |
| gptkbp:bfsParent |
gptkb:Kynurenine_pathway
gptkb:Tryptophan_metabolism |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
nicotinamide adenine dinucleotide (NAD+)
|