nicotinamide adenine dinucleotide (NAD+)
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:coenzyme
|
| gptkbp:abbreviation |
NAD+
|
| gptkbp:biosynthesized_from |
gptkb:nicotinic_acid
tryptophan nicotinamide |
| gptkbp:charge |
positive
|
| gptkbp:chemicalFormula |
C21H27N7O14P2
|
| gptkbp:component |
adenine
ribose nicotinamide phosphate group |
| gptkbp:discoveredBy |
gptkb:Arthur_Harden
William John Young |
| gptkbp:discoveredIn |
1906
|
| gptkbp:foundIn |
all living cells
|
| gptkbp:function |
redox reactions
electron capture substrate for enzymes |
| https://www.w3.org/2000/01/rdf-schema#label |
nicotinamide adenine dinucleotide (NAD+)
|
| gptkbp:involves |
oxidative phosphorylation
glycolysis cellular respiration citric acid cycle |
| gptkbp:IUPACName |
β-Nicotinamide adenine dinucleotide
|
| gptkbp:metabolism |
apoptosis
aging DNA repair signaling molecule mitochondrial function inflammation immune response gene expression regulation oxidative stress response energy transfer cell death neuroprotection circadian rhythm caloric restriction response accepts electrons donates electrons |
| gptkbp:molecularWeight |
663.43 g/mol
|
| gptkbp:oxidized_form |
NAD+
|
| gptkbp:predecessor |
niacin (vitamin B3)
|
| gptkbp:reduces |
gptkb:NADH
|
| gptkbp:used_by_enzyme |
sirtuins
dehydrogenase poly(ADP-ribose) polymerase |
| gptkbp:bfsParent |
gptkb:Kynurenine_pathway
gptkb:Tryptophan_metabolism |
| gptkbp:bfsLayer |
8
|